Breast cancer and background parenchymal enhancement at breast magnetic resonance imaging: a meta-analysis

BMC Medical Imaging

Jinghao Zhao¹  Quanshui Fu¹  Linwei Zhao¹  Hong Chen¹  Yong Li¹  Na Hu¹  Guoqing Yang¹  Wei Qin¹ 

[1] Department of Radiology, Suining Central Hospital;

关键词: Dynamic contrast-enhanced magnetic resonance imaging;    Breast magnetic resonance imaging;    Breast cancer;    Background parenchymal enhancement;   

DOI  :  10.1186/s12880-021-00566-8

来源: DOAJ

【 摘 要 】

Abstract Background The background parenchymal enhancement at breast magnetic resonance imaging use to predict breast cancer attracts many searchers to draw a possible relationship. However, the results of their relationships were conflicting. This meta-analysis was performed to assess breast cancer frequency associations with background parenchymal enhancement. Methods A systematic literature search up to January 2020 was performed to detect studies recording associations between breast cancer frequency and background parenchymal enhancement. We found thirteen studies including 13,788 women at the start with 4046 breast cancer. We calculated the odds ratio (OR) and the 95% confidence intervals (CIs) between breast cancer frequency and background parenchymal enhancement by the dichotomous technique with a random or fixed-effect model. Results Women with minimal or mild background parenchymal enhancement at breast magnetic resonance imaging did not have any risk of breast cancer compared to control women (OR, 1.20; 95% CI 0.54–2.67). However, high background parenchymal enhancement at breast magnetic resonance imaging (OR, 2.66; 95% CI 1.36–5.19) and moderate (OR, 2.51; 95% CI 1.49–4.21) was associated with a significantly higher rate of breast cancer frequency compared to control women. Conclusions Our meta-analysis showed that the women with high and moderate background parenchymal enhancement at breast magnetic resonance imaging have higher risks, up to 2.66 fold, of breast cancer. We suggest that women with high or moderate background parenchymal enhancement at breast magnetic resonance imaging to be scheduled for more frequent follow-up and screening for breast cancer to avoid any complications.

【 授权许可】

Unknown