Quinolone and Organophosphorus Insecticide Residues in Bivalves and Their Associated Risks in Taiwan

Molecules

Hsiao-Pei Tsai¹  Ching-Hung Chen²  Geng-Ruei Chang³  Chang-Hui Yeh³  Ching-Fen Wu³  Yao-Chi Su³  Pei-Shan Fan³  Wei-Cheng Yang⁴  Chen-Si Lin⁴  Ching-Yang Wu⁵  Ching-Feng Wu⁵ 

[1] College of Veterinary Medicine, Veterinary Teaching Hospital, National Chiayi University, 580 Xinmin Road, Chiayi 60054, Taiwan;Department of Anesthesiology, Show Chwan Memorial Hospital, 1 Section, 542 Chung-Shan Road, Changhua 50008, Taiwan;Department of Veterinary Medicine, National Chiayi University, 580 Xinmin Road, Chiayi 60054, Taiwan;Department of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, 4 Section. 1 Roosevelt Road, Taipei 10617, Taiwan;Division of Thoracic and Cardiovascular Surgery, Department of Surgery, Chang Gung University, Chang Gung Memorial Hospital, Linkou, 5 Fuxing Street., Guishan District, Taoyuan 33305, Taiwan;

关键词: quinolone;    organophosphorus pesticide;    residues;    bivalves;    risk assessment;   

DOI  :  10.3390/molecules25163636

来源: DOAJ

【 摘 要 】

Bivalves, such as freshwater clams (Corbicula fluminea) and hard clams (Meretrix lusoria), are the most extensive and widely grown shellfish in land-based ponds in Taiwan. However, few studies have examined the contamination of bivalves by quinolone and organophosphorus insecticides. Thus, we adapted an established procedure to analyze 8 quinolones and 12 organophosphorus insecticides using liquid and gas chromatography–tandem mass spectrometry. Surveys in Taiwan have not noted high residual levels of these chemicals in bivalve tissues. A total of 58 samples of freshwater or hard clams were obtained from Taiwanese aquafarms. We identified 0.03 mg/kg of enrofloxacin in one freshwater clam, 0.024 mg/kg of flumequine in one freshwater clam, 0.02 mg/kg of flumequine in one hard clam, 0.05 mg/kg of chlorpyrifos in one freshwater clam, 0.03 mg/kg of chlorpyrifos in one hard clam, and 0.02 mg/kg of trichlorfon in one hard clam. The results indicated that 5.17% of the samples had quinolone insecticide residues and 5.17% had organophosphorus residues. However, the estimated daily intake (EDI)/acceptable daily intake quotient (ADI) indicated no significant risk and no immediate health risk from the consumption of bivalves. These results provide a reference for the food-safety screening of veterinary drugs and pesticides in aquatic animals. Aquatic products should be frequently screened for residues of prohibited chemicals to safeguard human health.

【 授权许可】

Unknown