Antitumor effects of iridomyrmecin in HeLa cervical cancer cells are mediated via apoptosis induction, loss of mitochondrial membrane potential, cell cycle arrest and down-regulation of PI3K/Akt and up-regulation of lncRNA CCAT2 expression

Bangladesh Journal of Pharmacology

Min Liao¹  Ming-Zhe Li²  Tao Wang²  Min-Hai Dong²  Li Lin³  Xiao-Ling Cheng⁴  Zhen-Yu Wang⁵ 

[1] Department of Histology and Embryology, Institute of Neuroscience, Wenzhou Medical University, Wenzhou 325035;Department of Human Anatomy, Medical School, Wuhan University of Science and Technology, Wuhan, Hubei 430065;Division of Histology and Embryology, Department of Anatomy, Hubei University of Science and Technology, Xianning City, 437000;Institute of Biological Medicine, Wuhan University of Science and Technology, Wuhan, Hubei 430065;School of Medicine, Wuhan University of Science and Technology, Wuhan 430065;

关键词: Antitumor;    Apoptosis;    Cell cycle arrest;    HeLa cervical cancer cell;    Iridomyrmecin;    lncRNA CCAT2 expression;   

DOI  :  10.3329/bjp.v11i4.27539

来源: DOAJ

【 授权许可】

Unknown