Enantioselective synthesis of planar chiral ferrocenes via palladium-catalyzed annulation with diarylethynes

Beilstein Journal of Organic Chemistry

Yan-Chao Shi¹  Rong-Fei Yang¹  De-Wei Gao¹  Shu-Li You¹ 

[1] State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, China;

关键词: annulation;    asymmetric catalysis;    C–H activation;    ferrocene;    palladium;    planar chirality;   

DOI  :  10.3762/bjoc.9.222

来源: DOAJ

【 摘 要 】

When Boc-L-Val-OH was used as a ligand for the enantioselective Pd(II)-catalyzed annulation of N,N-substituted aminomethyl ferrocene derivatives with diarylethynes, ferrocenes with planar chirality could be achieved with excellent enantioselectivity (up to 99% ee).

【 授权许可】

Unknown