期刊论文详细信息
Medical Mycology Case Reports | |
The use of posaconazole delayed-release tablets in the successful treatment of suspected mucormycosis in a bottlenose dolphin (Tursiops truncatus) calf | |
Nuno U. Silva1  Gonçalo N. Marques2  Carla A. Flanagan3  Miriam O. Leal3  | |
[1] Zoomarine Portugal, N125 KM 65, 8201-864, Guia, Portugal;Corresponding author.;Zoomarine Portugal, N125 KM 65, 8201-864, Guia, Portugal; | |
关键词: Mucormycosis; Cunninghamella bertholettiae; Posaconazole; Bottlenose dolphin; Therapeutic drug monitoring; | |
DOI : | |
来源: DOAJ |
【 摘 要 】
Mucorales infections in cetaceans have a high mortality rate. This case report refers to a bottlenose dolphin calf with suspected mucormycosis treated with posaconazole. This antifungal agent was discontinued after 96 days of therapy, however, the infection relapsed. Posaconazole was then resumed for a total of 255 days, with no signs of disease reactivation. The retrospective analysis of posaconazole serum levels in this successful case showed concentrations varying between 5.18 and 11.63 mg/L.
【 授权许可】
Unknown