Spindle cell carcinoma of the breast as complex cystic lesion: a case report

Cancer Biology & Medicine

Keisuke Oikawa¹  Naoyuki Miyokawa¹  Kei Ishibashi¹  Satoshi Hayashi²  Yoshinari Matsuda²  Masahiro Kitada² 

[1] Department of Clinical Pathology, Asahikawa Medical University, Asahikawa Hokkaido 078-8510, Japan;Department of Surgery,;

关键词: Breast cancer;    spindle cell carcinoma;    cystic lesion;   

DOI  :  10.7497/j.issn.2095-3941.2014.02.008

来源: DOAJ

【 摘 要 】

Spindle cell carcinoma of the breast is a rare tumor. This tumor can proliferate rapidly and cause cystic changes because of internal tissue necrosis. We evaluated a 54-year-old woman with right breast lump. Mammography showed a category four mass with a diameter of 2.5 cm. Ultrasonography (US) revealed a complex cystic lesion, and fine-needle aspiration (FNA) cytology demonstrated bloody fluid and malignant cells. Partial breast resection and sentinel lymph node biopsy were performed. Immunohistology revealed spindle cells with positive results for cytokeratin (AE1/AE3) and vimentin, partially positive results for s-100, and negative results for desmin and α-actin. The pathological stage was ⅡA, and biochemical characterization showed that the tumor was triple negative. Six courses of FEC-100 chemotherapy (5-fluorouracil 500 mg/m², epirubicin 100 mg/m², and cyclophosphamide 500 mg/m²) were administered. Radiotherapy was performed. This case is discussed with reference to the literature.

【 授权许可】

Unknown