Relapses of urogenital tuberculosis

Tuberkulez i Bolezni Lëgkih

S. Yu. Shevchenko¹  E. V. Kulchavenya²  A. A. Baranchukova²  D. P. Kholtobin² 

[1] Novosibirsk State Medical University;Novosibirsk Tuberculosis Research Institute;

关键词: urogenital tuberculosis;    relapse;    incidence;    tuberculosis;    extrapulmonary tuberculosis;   

DOI  :  10.21292/2075-1230-2020-98-10-19-22

来源: DOAJ

【 摘 要 】

The objective of the study: to characterize the cases of tuberculosis relapses with lesion in urogenital organs.Subjects and methods. Out of 140 case histories of patients with urogenital tuberculosis (UGTB; tuberculosis of the urinary and male reproductive system), registered for follow-up by the phthisiourologist, all files of patients with tuberculosis relapses were picked up, totally, there were 13 of them.Results. Men prevailed among cases of relapses (61.5%). Patients at the age of 30-50 years old made 46.1%, and 53.9% were 51 years old and above. In the first episode of tuberculosis, lesions of the genitourinary system were observed in 53.9% of patients, bacterial excretion was found in 38.5%. On the average, the relapse developed in 9.1 years after successful cure of the first episode of tuberculosis: after respiratory tuberculosis – in 5.6 years and after UGTB – in 12.3 years. In 3 (23.1%) patients with relapse, mycobacteriuria was documented, in 1 of them, drug resistance (to streptomycin and isoniazid) was detected. In general, in the relapse of tuberculosis with urogenital lesions, the kidneys were most often (69.2%) affected. The treatment of relapse was effective in 12 out of 13 patients. During chemotherapy of tuberculosis, 3 (23.1%) patients developed toxic and allergic reactions that required treatment interruption or cancellation of the drug.

【 授权许可】

Unknown