In Newborn Infants a New Intubation Method May Reduce the Number of Intubation Attempts: A Randomized Pilot Study

Children

Georg M. Schmölzer¹  Stefan Heschl²  Lukas P. Mileder³  Bernhard Schwaberger³  Marlies Bruckner³  Christina H. Wolfsberger³  Nicholas M. Morris³  Gerhard Pichler³  Berndt Urlesberger³ 

[1] Centre for the Studies of Asphyxia and Resuscitation, Neonatal Research Unit, Royal Alexandra Hospital, 10240 Kingsway Avenue NW, Edmonton, AB T5H 3V9, Canada;Department of Anesthesiology and Intensive Care Medicine, Pediatric Anesthesia, Medical University of Graz, Auenbruggerplatz 34/2, 8036 Graz, Austria;Division of Neonatology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Auenbruggerplatz 34/2, 8036 Graz, Austria;

关键词: intubation;    endotracheal tube;    ventilation;    acute respiratory failure;    desaturation;    neonatal intensive care unit;   

DOI  :  10.3390/children8070553

来源: DOAJ

【 摘 要 】

Severe desaturation or bradycardia often occur during neonatal endotracheal intubation. Using continuous gas flow through the endotracheal tube might reduce the incidence of these events. We hypothesized that continuous gas flow through the endotracheal tube during nasotracheal intubation compared to standard nasotracheal intubation will reduce the number of intubation attempts in newborn infants. In a randomized controlled pilot study, neonates were either intubated with continuous gas flow through the endotracheal tube during intubation (intervention group) or no gas flow during intubation (control group). Recruitment was stopped early due to financial and organizational issues. A total of 16 infants and 39 intubation attempts were analyzed. The median (interquartile range) number of intubation attempts and number of abandoned intubations due to desaturation and/or bradycardia were 1 (1–2) and 4 (2–5), (p = 0.056) and n = 3 versus n = 20, (p = 0.060) in the intervention group and control group, respectively. Continuous gas flow through the endotracheal tube during intubation seems to be favorable and there are no major unexpected adverse consequences of attempting this methodology.

【 授权许可】

Unknown