The Promising Role of MicroRNAs, Long Non-Coding RNAs and Circular RNAs in Urological Malignancies

Translational Research in Urology

Helia Azodian Ghajar¹  Roghayeh Koohi Ortakand² 

[1] Department of Medical Genetics, Afzalipour Faculty of Medicine, Kerman University of Medical Sciences, Kerman, Iran;Hematology, Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences, Tehran, Iran;

关键词: non-coding rna;    ncrna;    lncrna;    mirna;    circrna;   

DOI  :  10.22034/TRU.2022.315706.1088

来源: DOAJ

【 摘 要 】

Nowadays, non-communicable diseases are the leading cause of death worldwide. Cancer management has been a significant challenge for public health in the last decade. Aging of the population and Urbanization have induced significant alters in population structure and increased burden of non-communicable diseases, like cancers. For several years, cancer genomics studies traditionally focused on coding genes. An explosion of studies into non-coding RNAs biology has shown that they could function as tumor suppressors and oncogenic drivers in nearly all cancer types. As a result, the uncovering of the role of functional RNAs in the formation and development of cancers is a promising frontier of cancer genetics.

【 授权许可】

Unknown