Translational Research in Urology | |
The Promising Role of MicroRNAs, Long Non-Coding RNAs and Circular RNAs in Urological Malignancies | |
Helia Azodian Ghajar1  Roghayeh Koohi Ortakand2  | |
[1] Department of Medical Genetics, Afzalipour Faculty of Medicine, Kerman University of Medical Sciences, Kerman, Iran;Hematology, Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences, Tehran, Iran; | |
关键词: non-coding rna; ncrna; lncrna; mirna; circrna; | |
DOI : 10.22034/TRU.2022.315706.1088 | |
来源: DOAJ |
【 摘 要 】
Nowadays, non-communicable diseases are the leading cause of death worldwide. Cancer management has been a significant challenge for public health in the last decade. Aging of the population and Urbanization have induced significant alters in population structure and increased burden of non-communicable diseases, like cancers. For several years, cancer genomics studies traditionally focused on coding genes. An explosion of studies into non-coding RNAs biology has shown that they could function as tumor suppressors and oncogenic drivers in nearly all cancer types. As a result, the uncovering of the role of functional RNAs in the formation and development of cancers is a promising frontier of cancer genetics.
【 授权许可】
Unknown