Characteristics of Clinical Isolates of Streptococcus mutans

Applied Sciences

Joanna Rudnicka¹  Ewa Iwanicka-Grzegorek¹  Renata Wolinowska²  Aleksandra Pisarska² 

[1] Department of Conservative Dentistry and Endodontics, Medical University of Warsaw, Binieckiego 6, 02-006 Warsaw, Poland;Department of Pharmaceutical Microbiology, Centre for Preclinical Research, Medical University of Warsaw, Banacha 1b, 02-097 Warsaw, Poland;

关键词: Streptococcus mutans;    caries;    biofilm;    dental plaque;    two-component systems (TCS);   

DOI  :  10.3390/app12094579

来源: DOAJ

【 摘 要 】

Dental caries is an infectious disease which remains a significant health problem all over the world. The purpose of the study was to characterise a collection of 60 clinical isolates of S. mutans from adults’ and children’s dental plaque (natural biofilm). The paper describes the process of isolation, identification, analysis of biofilm formation and collection testing for the presence of 13 two-component systems (TCS) identified earlier in reference strain ATCC 700610 (UA159). In the case of S. mutans strains, plaque formation is specifically influenced by binary systems. All isolated strains of S. mutans form biofilm at high levels and possess a set of 26 genes forming TSC binary systems, which have an important role in plaque formation.

【 授权许可】

Unknown