An Indole-Based Fluorescent Chemosensor for Detecting Zn2+ in Aqueous Media and Zebrafish

Sensors

Jiwon Kim¹  Ki-Tae Kim¹  Hangyul Lee²  Donghwan Choe²  Haeri So²  Cheal Kim²  Soyoung Park²  Ju Byeong Chae² 

[1] Department of Environmental Engineering, Seoul National University of Science and Technology (SNUT), Seoul 139-743, Korea;Department of Fine Chem and Renewable Energy Convergence, Seoul National University of Science and Technology (SNUT), Seoul 139-743, Korea;

关键词: zinc ion;    indole;    fluorescent chemosensor;    calculations;    bio-imaging;   

DOI  :  10.3390/s21165591

来源: DOAJ

【 摘 要 】

An indole-based fluorescent chemosensor IH-Sal was synthesized to detect Zn²⁺. IH-Sal displayed a marked fluorescence increment with Zn²⁺. The detection limit (0.41 μM) of IH-Sal for Zn²⁺ was greatly below that suggested by the World Health Organization. IH-Sal can quantify Zn²⁺ in real water samples. More significantly, IH-Sal could determine and depict the presence of Zn²⁺ in zebrafish. The detecting mechanism of IH-Sal toward Zn²⁺ was illustrated by fluorescence and UV–visible spectroscopy, DFT calculations, ¹H NMR titration and ESI mass.

【 授权许可】

Unknown