Design and synthesis of a novel rhodamine-based chemosensor and recognition study to Fe3+

Heterocyclic communications

article

Feifei Zhang¹  Qi Gao¹  Junxia Zhao¹  Man Ge¹  Yinjuan Bai¹ 

[1] Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, College of Chemistry and Materials Science, Northwest University

关键词: Fe3+;    fluorescent chemosensor;    fluorescence intensity;    spirolactam;   

DOI  :  10.1515/hc-2015-0139

学科分类：内科医学

来源: De Gruyter

【 摘 要 】

A fluorescent and colorimetric chemosensor Rh1 for Fe 3+ was synthesized by condensation reaction of rhodamine B hydrochloride and 2-aminothiazole, and its structure was confirmed by NMR, IR, HRMS and crystal data. Upon coordination with Fe 3+ in CH 3 CN-H 2 O (1:1, v/v) solution, the spirolactam of Rh1 is opened, which results in a dramatic enhancement of fluorescence intensity as well as the color change of the solution. Most importantly, other metal ions show no obvious interference with the detection of Fe 3+ . Under the optimum conditions described, the fluorescence intensity is linearly proportional to the concentration of Fe 3+ in the range of 2 μ m ~ 7 μ m . The Job’s plot indicates a 1:1 binding stoichiometry between Rh1 and Fe 3+ . The association constant (Ka) is 2.26 × 10 4 m -1 .

【 授权许可】

CC BY|CC BY-NC-ND