Sensitive SERS detection of melamine and cyromazine in raw milk using aptamer-based in situ silver nanoparticles synthesis

Results in Chemistry

Bowen Zheng¹  Haibo Xing²  Fuxiang Tian³  Xiaojun Hu³  Xu Dang³  Hongbo Zhang³  Xinyue Li³ 

[1] School of Chemical and Environmental Engineering, Shanghai Institute of Technology,Fengxian District, Shanghai 201418, China;Corresponding authors.;School of Chemical and Environmental Engineering, Shanghai Institute of Technology,Fengxian District, Shanghai 201418, China;

关键词: Aptamer;    SERS;    Cyromazine;    Melamine;    Simultaneous detection;   

DOI  :  

来源: DOAJ

【 摘 要 】

In this paper, we develop a simple design for simultaneous detection of melamine (MEL) and cyromazine (CYR) by surface-enhanced Raman scattering (SERS) with the formation of well-defined MEL or CYR-aptamer-AgNPs. This detection will take only 10 min, and SERS signals generated by MEL-aptamer-AgNPs exhibits a linear dependence on melamine (R2 = 0.998) concentration ranging from 0.1 to 0.5 ppm on melamine. The detection limit is sensitive down to 43.5 ppb. SERS signals generated by CYR-aptamer-AgNPs exhibits a linear dependence on cyromazine (R2 = 0.997) concentration ranging from 0.1 to 0.5 ppm on cyromazine. The detection limit is sensitive down to 23.6 ppb. This SERS biosensor was first reported for the simultaneous detection of melamine and cyromazine by using aptamer-based in situ silver nanoparticles synthesis. So we expected that the development of this biosensor could provide a good platform for the rapid detection of other pollutants in raw milk.

【 授权许可】

Unknown