Clinical characteristics and risk factors of patients with severe COVID-19 in Riyadh, Saudi Arabia: A retrospective study

Journal of Infection and Public Health

Fulwah Y. Alqahtani¹  Mana M. Alshehri²  Bahauddeen M. Alrfaei³  Hajar AlQahtani⁴  Ghalia Shamlan⁴  Maha M. Alrasheed⁵  Ahmed Alrashed⁶  Fadilah S. Aleanizy⁷  Marzouqah S. Alanazi⁷  Nassr Al-Maflehi⁸  Rania A.E.H. Mohamed⁹ 

[1] Corresponding author.;Federal Ministry of Health, Khartoum, Sudan;College of Science, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia;Department of Cellular Therapy and Cancer Research, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia;Department of Human Nutrition, College of Food Science and Agriculture, King Saud University, Riyadh 11362, Saudi Arabia;Department of Periodontics and Community Dentistry, College of Dentistry, King Saud University, Riyadh, Saudi Arabia;Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia;Department of Pharmacy Service, King Abdul-Aziz Medical City, Ministry of National Guard, Health Affairs, Riyadh, Saudi Arabia;Emergency Department, Prince Mohamed Bin Abdulaziz Hospital, Ministry of Health, Riyadh, Saudi Arabia;

关键词: Covid19;    Corona;    Severe COVID-19;    Risk factors;    Retrospective study;   

DOI  :  

来源: DOAJ

【 摘 要 】

Background: COVID-19 is newly emerging infectious disease that spread globally at unpredictable and unique pattern to the extent that the World Health Organization announced COVID-19 as a pandemic in the first couple months of 2020. This study aims to describe clinical and demographic features of COVID-19 patients and the influence of various risk factors on the severity of disease. Methods: This research is a retrospective study based on Saudi Arabia's ministry of health’s Covid-19 data. The analysis relies on data of all COVID-19 patients recorded in Riyadh between 1st, March 2020 and 30th, July 2020. Statistical analyses were performed to investigate the effect of demographic characteristic, clinical presentation, and comorbidities on infection severity. Results: A total number of 1026 COVID-19 patients were identified based on the demographic data as follows: 709 cases (69% of cases) were males and 559 cases (54% of cases) were Saudi. Most of patients were diagnosed with mild signs and symptoms 697 (68% of cases), while 164 patient (16% of cases) demonstrated moderate signs and symptoms, and 103 cases (10%) were severe and 62 (6%) had critical febrile illness. Fever, cough, sore throat, and shortness of breath were the most common symptoms among patients with COVID-19. Among studied comorbidities in COVID-19 patients, diabetes mellitus and hypertension were the most prevalent. The results from the bivariate logistic regression analysis revealed that older age, diabetes mellitus, asthma, smoking, and fever are associated with severe or critically ill cases. Conclusion: The findings of this study show that old age, fever, and comorbidities involving diabetes mellitus, asthma, and smoking were significantly associated with infection severity.

【 授权许可】

Unknown