Rate and Determinants of Recurrence at 1 Year and 5 Years After Stroke in a Low-Income Population in Rural China

Frontiers in Neurology

Lingling Bai¹  Wenjing Mao²  Jing Han³  Jun Tu⁵  Jie Liu⁵  Jinghua Wang⁵  Jingxian Ni⁵  Yanan Wu⁵  Xianjia Ning⁵  Min Shi⁵ 

[1] Department of Neurology, Liaocheng People's Hospital, Liaocheng, China;Department of Neurology, The Affiliated Hospital of North China University of Science and Technology, Tangshan, China;Department of Neurology, Tianjin Medical University General Hospital, Tianjin, China;Laboratory of Epidemiology, Tianjin Neurological Institute, Tianjin, China;Tianjin Neurological Institute, Key Laboratory of Post-Neuroinjury Neuro-repair and Regeneration in Central Nervous System, Ministry of Education and Tianjin City, Tianjin, China;

关键词: stroke;    recurrence;    predictors;    epidemiology;    incidence;   

DOI  :  10.3389/fneur.2020.00002

来源: DOAJ

【 摘 要 】

Recurrent stroke is becoming an increasingly important public health issue owing to the increased risk of disability and death. However, population-based studies investigating the rate of recurrent stroke in China are rare. We explored the rate and determinants of recurrent stroke within 1 and 5 years after the initial stroke in a rural population in China. Data for stroke events were obtained from the Tianjin Brain Study, conducted between 1992 and 2016. The age-standardized rates of recurrent stroke within the first year and the first 5 years after the initial stroke were calculated for this period. Determinants of recurrent stroke were assessed using Cox regression analyses. The overall age-standardized rate of recurrent stroke within 1 year was 5.7% (men, 6.9%; women, 4.6%); within 5 years, the overall recurrent stroke rate was 22.5% (men, 24.0%; women, 20.2%). The recurrence rate increased with advancing age and decreased with increased educational attainment. Age ≥65 years and a history of alcohol consumption were independent risk factors for recurrent stroke within 1 year after the incident stroke, after adjusting for age, sex, education, hypertension, diabetes, smoking, and alcohol consumption. However, the risk of recurrent stroke within 5 years after the incident stroke was positively associated with male sex, age ≥65 years, a lower level of education, known diabetes, and alcohol consumption, after adjusting for the previously indicated covariates. These findings suggest a crucial need to address risk factor management among stroke patients to reduce the burden of stroke, especially among low-income populations. Furthermore, a multicenter, large sample, nationwide study is urgently needed.

【 授权许可】

Unknown