Monte Carlo-based dose calculation for 32 P patch source for superficial brachytherapy applications

Journal of Medical Physics

关键词: 32 P patch;    brachytherapy;    dosimetry;    nafion;    skin cancer;   

DOI  :  10.4103/0971-6203.152232

来源: DOAJ

【 摘 要 】

Skin cancer treatment involving 32 P source is an easy, less expensive method of treatment limited to small and superficial lesions of approximately 1 mm deep. Bhabha Atomic Research Centre (BARC) has indigenously developed 32 P nafion-based patch source (1 cm Χ 1 cm) for treating skin cancer. For this source, the values of dose per unit activity at different depths including dose profiles in water are calculated using the EGSnrc-based Monte Carlo code system. For an initial activity of 1 Bq distributed in 1 cm 2 surface area of the source, the calculated central axis depth dose values are 3.62 Χ 10 -10 GyBq -1 and 8.41 Χ 10 -11 GyBq -1 at 0.0125 and 1 mm depths in water, respectively. Hence, the treatment time calculated for delivering therapeutic dose of 30 Gy at 1 mm depth along the central axis of the source involving 37 MBq activity is about 2.7 hrs.

【 授权许可】

Unknown