Intra-arterial thrombolysis for acute ischemic stroke: Our institutional experience

Indian Journal of Neurosurgery

卷:01

Rajesh Pati¹  Sibasankar Dalai² 

[1] ;

[2] Interventional Neuroradiology, Seven Hills Hospital;

关键词: acute stroke;    intra-arterial thrombolysis;    rtpa;    urokinase;   

DOI  :  10.4103/2277-9167.94369

来源: DOAJ

【 摘 要 】

IntroductionThe standard treatment for acute ischemic stroke is intravenous (IV) rtPA for patients who can reach the hospital within 3 to 4.5 h. There are case reports, where IA thrombolysis has helped patients in case an IV thrombolysis has failed. We report 14 cases of acute ischemic stroke treated by intra-arterial (IA) thrombolysis. Materials and MethodsWe have retrospectively analyzed 14 cases of acute ischemic stroke treated at our department between December 2008 and October 2011 by intra-arterial thrombolysis. The patients with suspected large vessel occlusion (11 patients) and patients not responding to IV rtPA (3 patients) were considered for the IA thrombolysis. ResultsWe achieved complete recanalization (TIMI 3) in 11 patients. One patient had a bleed following the procedure but recovered well during the hospital stay. All the patients were followed up to 90 days. Majority of them have good functional outcome. ConclusionsOur study suggests that intra-arterial thrombolysis is a feasible option in the subgroup of patients with large vessel occlusion. However, there is a need for a randomized multicentric study to support our results.

【 授权许可】

Unknown