COVID-19 among Healthcare Workers: A Prospective Serological-Epidemiological Cohort Study in a Standard Care Hospital in Rural Germany

International Journal of Environmental Research and Public Health

卷:18

Stephanie Hoffmann¹  Jacob Spallek¹  Juliane Schiebel²  Heinz-Detlef Gremmels²  Frank Hufert³ 

[1] Department of Public Health, Institute of Health, Brandenburg University of Technology Cottbus-Senftenberg, 01968 Senftenberg, Germany;

[2] Institute for Clinical Chemistry, Laboratory Diagnostics and Microbiology, Klinikum Niederlausitz GmbH, 01968 Senftenberg, Germany;

[3] Institute of Microbiology and Virology, Brandenburg Medical School Theodor Fontane, 01968 Senftenberg, Germany;

关键词: SARS-CoV-2;    immunity;    antibody;    healthcare;    staff;    COVID-19;   

DOI  :  10.3390/ijerph182010999

来源: DOAJ

【 摘 要 】

Healthcare workers (HCW) play a vital role in the SARS-CoV-2 pandemic control. The aim of this study was to assess the prevalence of SARS-CoV-2 antibodies and the risk of COVID-19 infections in a cohort of HCW from four different risk groups (from intensive care unit to administration) of a hospital of a primary care level in rural Germany. The outcomes were monthly measures of antibody seroprevalence over a period of 6 months. Overall, a seroprevalence of 13.41% was determined, with significantly higher prevalence rates among HCW working in areas with more frequent contact to confirmed or suspected cases (30.30%, p = 0.003). The group specific differences in the risk of infection from COVID-19 were detected, as HCW groups with frequent exposure seemed to have an increased risk (RR = 3.18, p = 0.02; CI95 1.09–9.24). The findings contribute to the epidemiological understanding of the virus spread in an unvaccinated population group, which is highly relevant for the pandemic management.

【 授权许可】

Unknown