Effects of dietary inactivated probiotics on growth performance andimmune responses of weaned pigs

Journal of Animal Science and Technology

卷:63

Sung Hun Kim¹  Hyeun Bum Kim²  Jeehwan Choe³  Hyunjin Kyoung⁴  Joowon Kang⁴  Jeong Jae Lee⁴  Minho Song⁴  Jin Ho Cho⁵ 

[1] CJ CheilJedang Corporation, ;

[2] Department of Animal Resource, DankookUniversity, ;

[3] Department of Beef Science, Korea NationalCollage of Agriculture and Fisheries, ;

[4] Division of Animal and Dairy Science,Chungnam National University, ;

[5] Division of Food and Animal Science,Chungbuk National University, ;

关键词: diarrhea;    growth performance;    heat-killed lactobacillus rhamnosus;    immune responses;    inactivated probiotics;    weaned pigs;   

DOI  :  10.5187/jast.2021.e44

来源: DOAJ

【 摘 要 】

This experiment was performed to verify whether dietary heat-killedLactobacillus rhamnosus (LR) improves growth performanceand modulates immune responses of weaned pigs. Ninety-six weaned pigs ([Landrace× Yorkshire] × Duroc; 6.95 ± 0.25 kg body weight [BW]; 28 dold) were randomly allocated to four treatments: 1) a basal diet withoutheat-killed LR (CON), 2) T1 (CON with 0.1% heat-killed LR), 3) T2 (CON with 0.2%heat-killed LR), and 4) T3 (CON with 0.4% heat-killed LR). Each treatment hadsix pens with four pigs (6 replicates per treatment) in a randomized completelyblock design. The heat-killed LR used in this study contained 1 ×109 FU/g of LR in a commercial product. Pigs were fed eachtreatment for four weeks using a two-phase feeding program to measure growthperformance and frequency of diarrhea. During the last week of this study, alldiets contained 0.2% chromic oxide as an indigestible marker. Fecal sampling wasperformed through rectal palpation for the consecutive three days after the fouradaptation days to measure apparent total tract digestibility (ATTD) of drymatter, crude protein, and gross energy (GE). Blood sampling was also performedon day 1, 3, 7, and 14 after weaning to measure immune responses such as serumtumor necrosis factor-α (TNF-α), transforming growthfactor-β1 (TGF-β1), C-reactive protein (CRP), and cortisol. Theheat-killed LR increased (p < 0.05) growth rate, feedefficiency, and ATTD of GE for overall experimental period compared with CON,but reduced (p < 0.05) post-weaning diarrhea. Inaddition, pigs fed diets contained heat-killed had lower concentrations of serumTNF-α (d 7; p < 0.05), TGF-β1 (d 7;p < 0.10), and cortisol (d 3 and 7;p < 0.05) than pigs fed CON. In conclusion, dietaryheat-killed LR improved growth rate, modified immune responses of weaned pigs,and alleviated post-weaning diarrhea.

【 授权许可】

Unknown