A brief review of exercise, bipolar disorder and mechanistic pathways

Frontiers in Psychology

卷:6

Lesley eBerk¹  Ajeet B Singh¹  Sue eLauder²  Louisa eSylvia⁴  Margaret E Gigler⁵  Michael eBerk⁶  Daniel eThomson⁷  Julie ePasco⁸  Alyna eTurner⁸ 

[1] Deakin University;

[2] Federation University;

[3] Florey Institute for Neuroscience and Mental Health;

[4] Harvard University;

[5] Massachusetts General Hospital;

[6] Orygen, The National Centre of Excellence in Youth Mental Health;

[7] RMIT;

[8] University of Melbourne;

[9] University of Newcastle;

关键词: Bipolar Disorder;    Depression;    Exercise;    Neurogenesis;    hypomania;    Mechanistic pathways;   

DOI  :  10.3389/fpsyg.2015.00147

来源: DOAJ

【 摘 要 】

Despite evidence that exercise has been found to be effective in the treatment of depression, it is unclear whether these data can be extrapolated to bipolar disorder. Available evidence for bipolar disorder is scant, with no existing randomised controlled trials having tested the impact of exercise on depressive, manic or hypomanic symptomatology. Although exercise is often recommended in bipolar disorder, this is based on extrapolation from the unipolar literature, theory and clinical expertise and not empirical evidence. In addition, there are currently no available empirical data on program variables, with practical implications on frequency, intensity and type of exercise derived from unipolar depression studies. The aim of the current paper is to explore the relationship between exercise and bipolar disorder and potential mechanistic pathways.Given the high rate of medical co-morbidities experienced by people with bipolar disorder, it is possible that exercise is a potentially useful and important intervention with regard to general health benefits; however, further research is required to elucidate the impact of exercise on mood symptomology.

【 授权许可】

Unknown