Markers for hepatic autoimmune disorders in patients with type 1 diabetes mellitus

Сахарный диабет

卷:17

Olga Nikolaevna Ivanova¹  Olga Sergeevna Derevyanko¹  Nadejda Sergeevna Dalantaeva¹  Olga Mikhailovna Smirnova¹  Nikolay Petrovich Goncharov¹  Tatiana Vasil'evna Nikonova¹ 

[1] Endocrinology Research Centre;

关键词: type 1 diabetes mellitus;    autoimmune hepatitis;    autoantibodies;   

DOI  :  10.14341/DM2014129-33

来源: DOAJ

【 摘 要 】

Aim.To assess the occurrence of autoantibodies characteristic of autoimmune hepatitis in patients with type 1 diabetes mellitus (T1DM), and to analyze clinical features of positive subjects. Materials and Methods.. 84 patients (39 male, 45 female) with T1DM were subdivided into two groups and underwent biochemical, immunologic and instrumental examination. Results.Markers for hepatic autoimmune disorders were found to be highly prevalent in patients with T1DM, even in those asymptomatic according to clinical and instrumental diagnostic methods. Conclusion. Our data suggests that T1DM patients are at higher risk of corresponding, though possibly asymptomatic autoimmune disorders.

【 授权许可】

Unknown