CLINICAL DIAGNOSTIC VALUE OF AUTOANTIBODIES IN THE DIAGNOSIS OF AUTOIMMUNE LIVER DISEASES

Medicinskaâ Immunologiâ

V. V. Bazarnyi¹  E. Yu. Mikhailova¹  E. A. Partylova¹ 

[1] Ural State Medical University620028, Russian Federation, Ekaterinburg, Repin str., 3.;

关键词: autoimmune hepatitis;    primary biliary cirrhosis;    autoantibodies;   

DOI  :  10.15789/1563-0625-2015-1-93-96

来源: DOAJ

【 摘 要 】

We are studied the 15 patients with autoimmune liver diseases and 36 patients without autoimmune pathology found the diagnostic value of antinuclear and antimitochondrial autoantibodies (AMA-M2) tests, and antibodies to asialoglycoprotein receptor (anti-ASGPR). Based on the ROC analysis showed that the diagnostic sensitivity and diagnostic specificity of AMA-M2 was 73% and 100% and for anti-ASGPR – 60% and 77%, respectively. Therefore, the test for anti-ASGPR in autoimmune diseases of the liver showed no advantages over standart tests, and its using in clinical practice requires clarification.

【 授权许可】

Unknown