Mucosa-associated lymphoid tissue lymphoma of the trachea: case report

São Paulo Medical Journal

卷:130

Carlos Alberto da Conceição Lima¹  Maria Elisa Ruffolo Magliari²  Renata Telles Rudge de Aquino²  Carlos Sérgio Chiattone²  Joaquim Antonio da Fonseca Almeida²  Benedito Juarez Andrade²  Fabíola del Carlo Bernardi²  Fábio Marioni²  Anna Luiza Lobão Gonçalves²  Sérgio Brasil² 

[1] Faculdade de Ciências Médicas da Santa Casa de São Paulo;

[2] Irmandade da Santa Casa de Misericórdia de São Paulo;

关键词: Lymphoma;    B-Cell;    marginal zone;    Neoplasms;    Tracheal neoplasms;    Lymphoma;    Lymphoma;    non-Hodgkin;   

DOI  :  10.1590/S1516-31802012000200010

来源: DOAJ

【 摘 要 】

CONTEXT: Mucosa-associated lymphoid tissue (MALT) lymphomas are most commonly found in the stomach, lungs, orbital soft tissue, salivary glands and thyroid. Involvement of the trachea is extremely rare. CASE REPORT: This report describes a rare case of MALT lymphoma of the trachea in a 71-year-old woman who presented with a one-year history of coughing, dyspnea, hoarseness and weight loss. There was an infiltrative lesion in the mid-trachea. The anatomopathological diagnosis was only made from the fifth endoscopic biopsy attempt. Immunochemotherapy consisting of rituximab, cyclophosphamide, vincristine and prednisone (R-COP) induced complete remission of the symptoms and endoscopic lesion. CONCLUSIONS: MALT lymphoma of the trachea is extremely rare and indolent disease. It has to be considered in the differential diagnosis of airway lesions. It is crucial to obtain an anatomopathological diagnosis from a specialized pathologist. Immunochemotherapy with R-COP induced complete remission of the disease.

【 授权许可】

Unknown