Mucosa-associated lymphoid tissue lymphoma of the trachea: case report

Sao Paulo Medical Journal

Maria Elisa Ruffolo Magliari²  Renata Telles Rudge De Aquino¹  Anna Luiza Lobão Gonçalves¹  Fábio Marioni¹  Fabíola Del Carlo Bernardi¹  Sérgio Brasil¹  Joaquim Antonio Da Fonseca Almeida¹  Benedito Juarez Andrade¹  Carlos Sérgio Chiattone¹  Carlos Alberto Da Conceição Lima¹ 

[1] ,Santa Casa de São Paulo Faculdade de Ciências Médicas Department of Clinical MedicineSão Paulo,Brazil

关键词: Lymphoma;    B-Cell;    marginal zone;    Neoplasms;    Tracheal neoplasms;    Lymphoma;    Lymphoma;    non-Hodgkin;    Linfoma de zona marginal tipo células B;    Neoplasias;    Neoplasias da traquéia;    Linfoma;    Linfoma não Hodgkin;   

DOI  :  10.1590/S1516-31802012000200010

来源: SciELO

【 摘 要 】

CONTEXT: Mucosa-associated lymphoid tissue (MALT) lymphomas are most commonly found in the stomach, lungs, orbital soft tissue, salivary glands and thyroid. Involvement of the trachea is extremely rare. CASE REPORT: This report describes a rare case of MALT lymphoma of the trachea in a 71-year-old woman who presented with a one-year history of coughing, dyspnea, hoarseness and weight loss. There was an infiltrative lesion in the mid-trachea. The anatomopathological diagnosis was only made from the fifth endoscopic biopsy attempt. Immunochemotherapy consisting of rituximab, cyclophosphamide, vincristine and prednisone (R-COP) induced complete remission of the symptoms and endoscopic lesion. CONCLUSIONS: MALT lymphoma of the trachea is extremely rare and indolent disease. It has to be considered in the differential diagnosis of airway lesions. It is crucial to obtain an anatomopathological diagnosis from a specialized pathologist. Immunochemotherapy with R-COP induced complete remission of the disease.

【 授权许可】

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