Kinetic modeling of the alkaline deproteinization of Nile-tilapia skin for the production of collagen

Heliyon

卷:6

Luis Alberto Rios¹  José Edgar Zapata-Montoya²  Diego Enrique Giraldo-Rios³ 

[1]Corresponding author.

[2]|Grupo Procesos Químicos Industriales, Facultad de Ingeniería, Universidad de Antioquia U de A, Calle 7052-21, Medellín, Colombia

[3]|Grupo de Nutrición y Tecnología de Alimentos, Facultad de Ciencias Farmacéuticas y Alimentarias, Universidad de Antioquia U de A, Calle 7052-21, Medellín, Colombia

关键词: Chemical engineering;    Dynamical system;    Transport process;    Materials characterization;    Chemical reaction kinetics;    Chemical characterization of food;   

DOI  :  

来源: DOAJ

【 摘 要 】

A new phenomenological model, based on a second order dissolution kinetics, was developed for the alkaline removal of non-collagenous protein (NCP) from the skin of Nile tilapia (SNT). This model allows estimating the liquid concentration of NCP in terms of temperature, skin size, NaOH concentration and time. This model was fitted with 135 experiments averaging a R2 of 0.99. The root-mean-square deviation and the mean-absolute-percentage error of the model were 0.0041 and 3.15%, respectively. The Arrhenius-activation energy was 15–122 kJ mol−1. Multi-objective optimization led to the highest NCP extraction (NCPE) of 24.3% and to the lowest loss of collagen (LC) of 1.3%, with R2 coefficients of 0.98 and 0.92, respectively. Ultimately, SNT deproteinized under optimal conditions was subjected to acid extraction and purification. FTIR and SEM analyses indicated that the product was a Type I collagen that could be used in the pharmaceutical industry.

【 授权许可】

Unknown