Genetic Variability of Koi Herpesvirus In vitro—A Natural Event?

Frontiers in Microbiology

卷:8

Jolanta Kempter¹  Pei-Yu Lee²  Sven M. Bergmann³  Sandro Klafack³  Marek Matras⁴  Yingying Li⁵  Shucheng Zheng⁵  Yingying Wang⁵  Weiwei Zeng⁵  Qing Wang⁵ 

[1] Department of Aquaculture, West Pomeranian University of TechnologySzczecin, Poland;

[2] Department of Research and Development, GeneReach Biotechnology CorporationTaichung, China;

[3] Friedrich-Loeffler-Institut, Federal Research Institute for Animal HealthGreifswald-Insel Riems, Germany;

[4] National Veterinary Research InstitutePulawy, Poland;

[5] Pearl River Fisheries Research Institute, Chinese Academy of Fishery SciencesGuangzhou, China;

关键词: KHV;    VNTR;    Cyprinus carpio;    molecular tracing;    CyHV3;   

DOI  :  10.3389/fmicb.2017.00982

来源: DOAJ

【 摘 要 】

Worldwide koi herpesvirus (KHV) causes high mortalities in Cyprinus carpio L. aquaculture. So far, it is unknown how the different variants of KHV have developed and how they spread in the fish, but also in the environmental water bodies. Therefore, a phylogenetic method based on variable number of tandem repeats (VNTR) was improved to gain deeper insights into the phylogeny of KHV and its possible worldwide distribution. Moreover, a VNTR-3 qPCR was designed which allows fast virus typing. This study presents a useful method for molecular tracing of diverse KHV types, variants, and lineages.

【 授权许可】

Unknown