Gut-thyroid axis and celiac disease

Endocrine Connections

卷:6

Patricia Jeremias¹  Torsten Matthias²  Aaron Lerner³ 

[1] AESKU.KIPP Institute, Wendelsheim, Germany;

[2] B. Rappaport School of Medicine, Technion-Israel Institute of Technology, Haifa, Israel;

关键词: intestine;    thyroid;    celiac disease;    Hashimoto’s thyroiditis;    autoimmunity;   

DOI  :  10.1530/EC-17-0021

来源: DOAJ

【 摘 要 】

Autoimmune thyroiditis has an increased prevalence in patients with celiac disease and vice versa. The objective of the current review is to highlight the epidemiological, clinical, serological, pathological, pathophysiological, hormonal, genetic and immunological factors shared between the two entities. They might represent the two ends of the gut-thyroid axis where the cross-talks’ pathways are still unravelled. New observations are reviewed, highlighting some gut-thyroid interrelated pathways that potentially might lead to new therapeutic strategies.

【 授权许可】

Unknown