Understanding cavitation-related mechanism of therapeutic ultrasound in the field of urology: Part I of therapeutic ultrasound in urology

Investigative and Clinical Urology

卷:63

Hyunjae Song¹  Sung Yong Cho²  Min Joo Choi³  Seong-Chan Kim³  Ohbin Kwon³  Kanghae Kim³ 

[1] Department of Electronic Engineering, Sogang University, Seoul, Korea.;

[2] Department of Urology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.;

[3] Interdisciplinary Postgraduate Program in Biomedical Engineering, Jeju National University, Jeju, Korea.;

关键词: acoustic waves;    eswl (extracorporeal shockwave lithotripsy);    laser-induced shockwave lithotripsy;    lasers;    solid-state;    photography;   

DOI  :  10.4111/icu.20220059

来源: DOAJ

【 摘 要 】

Shock waves are commonly used in the field of urology. They have two phases, positive and negative, and the bubble generation is roughly classified into acoustic cavitation (AC) and laser-induced cavitation (LIC). We evaluated the occurrence of cavitation, its duration, the area of interest, and the maximal diameter of the cavitation bubbles. Changes in AC occurred at 0.2 ms with the highest number of bubbles and disappeared at 0.6 ms. The bubble size was 2 mm in diameter. Changes in LIC bubbles were observed in three pulse modes. The short pulse showed an initial bubble starting at 0.005 ms, which reached its largest size at 0.4 to 0.6 ms. The long pulse showed an initial bubble starting at 0.005 ms, which reached its largest size at 0.4 ms with the formation of an additional lagena-shaped bubble at 0.6 ms. The distance mode of MOSES showed two signal peaks with the formation of two consecutive bubbles at 0.2 and 0.6 ms. The main difference in the laser beams between the long-pulse and the MOSES modes was the continuity and the peak power of the laser beam. The diameters parallel to the laser direction were 6.8, 8.6, and 9.7 mm at 1, 2, and 3 J, respectively, in the short pulse. While the cavitation bubbles rupture, ejectile force occurs in numerous directions, transmitting high enough energy to break the targets. Cavitation bubbles should be regarded as energy and the mediators of energy for stone fragmentation and tissue destruction.

【 授权许可】

Unknown