Malnutrition and Poor Physical Function Are Associated With Higher Comorbidity Index in Hospitalized Older Adults

Frontiers in Nutrition

卷:9

Ana Rodriguez-Larrad²  Miriam Urquiza²  Maria Amasene³  Iñaki Echeverria⁴  Idoia Labayen⁶  María Medrano⁶  Besga-Basterra Ariadna⁷  Amaia Diez⁸ 

[1] Ageing and Frailty Research Group, Bioaraba Health Research Institute, Vitoria-Gasteiz, Spain;

[2] Biocruces Bizkaia Health Research Institute, Barakaldo, Spain;

[3] Department of Pharmacy and Food Science, University of the Basque Country UPV/EHU, Vitoria-Gasteiz, Spain;

[4] Department of Physical Education and Sport, University of the Basque Country, Vitoria-Gasteiz, Spain;

[5] Department of Physiology, University of the Basque Country, UPV/EHU, Leioa, Spain;

[6] Institute on Innovation and Sustainable Development in Food Chain (IS-FOOD), Public University of Navarre (UPNA), Pamplona, Spain;

[7] Internal Medicine Department, Osakidetza Basque Health Service, Araba University Hospital, Vitoria-Gasteiz, Spain;

[8] Nurse Supervisor, Bioaraba Research Institute, Araba University Hospital, Vitoria-Gasteiz, Spain;

关键词: chronic diseases;    geriatrics;    inpatients;    nutritional status;    muscle strength;    mortality;   

DOI  :  10.3389/fnut.2022.920485

来源: DOAJ

【 摘 要 】

BackgroundThe Charlson Comorbidity Index (CCI) is the most widely used method to measure comorbidity and predict mortality. There is no evidence whether malnutrition and/or poor physical function are associated with higher CCI in hospitalized patients. Therefore, this study aimed to (i) analyze the association between the CCI with nutritional status and with physical function of hospitalized older adults and (ii) examine the individual and combined associations of nutritional status and physical function of older inpatients with comorbidity risk.MethodsA total of 597 hospitalized older adults (84.3 ± 6.8 years, 50.3% women) were assessed for CCI, nutritional status (the Mini Nutritional Assessment-Short Form [MNA-SF]), and physical function (handgrip strength and the Short Physical Performance Battery [SPPB]).ResultsBetter nutritional status (p < 0.05) and performance with handgrip strength and the SPPB were significantly associated with lower CCI scores among both men (p < 0.005) and women (p < 0.001). Patients with malnutrition or risk of malnutrition (OR: 2.165, 95% CI: 1.408–3.331, p < 0.001) as well as frailty (OR: 3.918, 95% CI: 2.326–6.600, p < 0.001) had significantly increased the risk for being at severe risk of comorbidity. Patients at risk of malnutrition or that are malnourished had higher CCI scores regardless of being fit or unfit according to handgrip strength (p for trend < 0.05), and patients classified as frail had higher CCI despite their nutritional status (p for trend < 0.001).ConclusionsThe current study reinforces the use of the MNA-SF and the SPPB in geriatric hospital patients as they might help to predict poor clinical outcomes and thus indirectly predict post-discharge mortality risk.

【 授权许可】

Unknown