Nanoscale Research Letters | 卷:12 |
Enhanced Biocompatibility in Anodic TaO x Nanotube Arrays | |
Her-Hsiung Huang1  Chien-Ying Wang2  Yen-Bin Hsu3  Ming-Ying Lan3  Sheng-Chen Twan4  Kuan-Wen Wang4  Yu-Jin Zeng4  Sheng-Wei Lee4  | |
[1] Department of Dentistry, National Yang-Ming University; | |
[2] Department of Emergency, Taipei Veterans General Hospital; | |
[3] Department of Otolaryngology Head and Neck Surgery, Taipei Veterans General Hospital; | |
[4] Institute of Materials Science and Engineering, National Central University; | |
关键词: Biocompatibility; TaO x nanotubes; Anodic oxidation; Hydrophilicity; Human fibroblast cells; | |
DOI : 10.1186/s11671-017-2325-0 | |
来源: DOAJ |
【 摘 要 】
Abstract This study first investigates the biocompatibility of self-organized TaO x nanotube arrays with different nanotube diameters fabricated by electrochemical anodization. All as-anodized TaO x nanotubes were identified to be an amorphous phase. The transition in surface wettability with TaO x nanotube diameters can be explained based on Wenzel’s model in terms of geometric roughness. In vitro biocompatibility evaluation further indicates that fibroblast cells exhibit an obvious wettability-dependent behavior on the TaO x nanotubes. The 35-nm-diameter TaO x nanotube arrays reveal the highest biocompatibility among all samples. This enhancement could be attributed to highly dense focal points provided by TaO x nanotubes due to higher surface hydrophilicity. This work demonstrates that the biocompatibility in Ta can be improved by forming TaO x nanotube arrays on the surface with appropriate nanotube diameter and geometric roughness.
【 授权许可】
Unknown