Photodynamic therapy of penile cancer

Biomedical Photonics

卷:9

G. P. Gens¹  A. V. Tikhonenko¹  D. M. Yagudaev²  Z. A. Kadyrov²  N. A. Kalyagina³ 

[1] Moscow State University of Medicine and Dentistry named after A.I. Evdokimov;

[2] Peoples’ Friendship University of Russia;

[3] Prokhorov General Physics Institute of the Russian Academy of Sciences;

关键词: penile cancer;    photodynamic therapy;    fotoditazin;   

DOI  :  10.24931/2413-9432-2020-9-1-42-46

来源: DOAJ

【 摘 要 】

In this article we submit the case report of a patient with cT1N0M0 penile cancer diagnosis. The patient underwent two courses of photodynamic therapy (PDT) using Fotoditazin photosensitizer (PS) and ATKUS-2 diode laser. The PS was administered at a dose of 1 mg/kg of body weight 2 hours prior to the PDT session. The irradiation parameters were: 662 nm laser wavelength, 200 mW/cm2 power density and 250 J/cm2 energy density. In the presented clinical observation, we demonstrated that PDT is an effective and safe treatment method in patients with non-invasive penile cancer. The use of photodynamic therapy allowed preserving the physiological urination, sexual function and achieving a good cosmetic effect.

【 授权许可】

Unknown