Cytological effects in lymph nodes of abdominal lymphodissection zone after intraoperative photodynamic therapy of gastrointestinal cancers

Biomedical Photonics

E. S. Pirozhenko¹  U. A. Drozd²  V. Yu. Kravtsov³  K. V. Pavelec³  M. A. Protchenkov⁴ 

[1] North-Western State Medical University named after I.I. Mechnikov, Saint-Petersburg;Saint-Petersburg State Pediatric Medical University, Saint-Petersburg;Military Medical Academy of S.M. Kirov, Saint-Petersburg;North-Western State Medical University named after I.I. Mechnikov, Saint-Petersburg;

关键词: photodynamic therapy;    cytopathology;    interphase nucleus;    apoptosis;    radachlorin;    fotoditazin;   

DOI  :  10.24931/2413-9432-2018-7-4-11-15

来源: DOAJ

【 摘 要 】

Cytological studies on lymph nodes of abdominal lymphodissection zone after local intraoperative photodynamic therapy (IOPDT) of gastrointestinal cancers were carried out. As a result of the PDT, the metastatic cells are destroyed, their cytoplasmic membranes and the cytoplasm disappears, leaving behind interphase nuclei ("naked nuclei") (p<0,0001). Cytological confrmation of apoptosis (the presence of apoptotic bodies) in metastatic lymph nodes after IOPDT sessions on the lymph nodes of the abdominal lymphodissection zone is also presented.

【 授权许可】

Unknown