Neonatal body composition: crossectional study in healthy term singletons in Germany

BMC Pediatrics

卷:19

Christoph Maas¹  Romy Weber¹  Axel R. Franz¹  Lena Balles¹  Cornelia Wiechers¹  Vanessa Avelina¹  Sara Kirchhof¹  Christian F. Poets¹  Jan Pauluschke-Fröhlich²  Hubert Preißl³  Andreas Fritsche³  Manfred Hallschmid⁴ 

[1] Department of Neonatology, University Children’s Hospital, Eberhard Karls University;

[2] Department of Obstetrics and Gynecology, University Hospital, Eberhard Karls University;

[3] German Center for Diabetes Research, Eberhard Karls University;

[4] Institute for Medical Psychology and Behavioural Neurobiology, Eberhard Karls University;

关键词: Infant;    Neonatal;    Body composition;    Air displacement plethysmography;    Fat mass;   

DOI  :  10.1186/s12887-019-1837-4

来源: DOAJ

【 摘 要 】

Abstract Background During pregnancy, a variety of factors can influence fetal growth and development. Intrauterine growth may impact on later life and health. Neonatal body composition may be a more sensitive marker for the intrauterine environment than established anthropometric parameters at birth. Methods To study neonatal body composition determined by air displacement plethysmography in healthy, term singletons as national reference data, and to establish factors impacting on neonatal body composition in this population. This prospective cross-sectional observational study included 271 healthy, full-term, singletons born between June 2014 and July 2015. Body composition was measured within 96 h of birth using air displacement plethysmography. Results Median (Q1, Q2) fat mass / total body mass (BF%) in German singletons was 10.8% (7.7–13.4) and fat free mass (FFM) 2843 g (2606–3099). Female infants had significantly increased BF% compared to male infants (11.2% (8.7–14.0) vs. 9.6% (7.2–12.1)). On multiple regression analysis, BF% and fat mass increased with female gender, maternal pre-pregnancy body mass index, non-smoking mother and parity, whereas FFM increased with male gender and increasing gestational age at birth. Gestational weight gain category, birth mode, and postnatal age at measurement were not associated with BF%, FFM or fat mass. Conclusions We generated BF% and FFM centiles for healthy, term, singletons born in Germany; these are similar to those found in other European countries. Infant body composition at birth was associated with modifiable (pre-pregnancy body mass index, smoking), and given factors (gender, gestational age at birth, parity).

【 授权许可】

Unknown