Multicentric Atrial Strain COmparison between Two Different Modalities: MASCOT HIT Study

Diagnostics

卷:10

Julien Magne¹  Anja Zupan Mežnar²  Federica Ilardi³  Raluca Dulgheru³  Doralisa Morrone⁴  Iacopo Fabiani⁴  Asim Katbeh⁵  Martin Penicka⁵  Thor Edvardsen⁶  Erwan Donal⁷  Elena Galli⁷  AndreeaIulia Motoc⁸  Bernard Cosyns⁸  Roberta Esposito⁹  Ciro Santoro⁹  Maurizio Galderisi⁹  Denisa Muraru¹⁰  Giuseppe Sammarco¹⁰  Philippe Mortelmans¹¹  CarolineM. Van De Heyning¹¹  Tor Biering-Sørensen¹²  FlemmingJavier Olsen¹²  Guillem Casas¹³  Laura Galian-Gay¹³  Tomas Lapinskas¹⁴  JolantaJustina Vaškelyté¹⁴  Blazej Michalski¹⁵  Karolina Kupczynska¹⁵  Sorina Mihaila Baldea¹⁶  Dragos Vinereanu¹⁶  BogdanA. Popescu¹⁷  Vlatka Reskovic Luksic¹⁸  Dosen Dejan¹⁸  Katja Ažman Juvan¹⁹  Augustine Coisne²⁰  Amandine Coppin²⁰  Gergely Ágoston²¹  Istvan Szabó²¹  MariaConcetta Pastore²²  Sergio Mondillo²²  GiuliaElena Mandoli²²  Matteo Cameli²²  SvetlinNetkov Tsonev²³  Krasimira Hristova²³  Artem Kalinin²⁴  Žanna Pičkure²⁴  Riitta Paakkanen²⁵  DanOctavian Nistor²⁶  MihaelaMaria Opris²⁶  Leonardo Griseli²⁷  MarceloHaertel Miglioranza²⁷  Savvas Loizos²⁸  ConstantinosHristou Papadopoulos²⁸  Alessandro Salustri²⁹  Galal Abushahba²⁹  Fiorella Devito³⁰  Giovanni Benfari³¹  Giovanna Di Giannuario³²  Roberta Ancona³³  Salvatore Comenale Pinto³³  Gerolamo Sibilio³³ 

[1] CHU Limoges, Hôpital Dupuytren, Service Cardiologie, F-87042, 87042 Limoges, France;

[2] Cardiology Department, University Medical Centre Ljubljana, 1000 Ljubljana, Slovenia;

[3] Cardiology Department—Heart Valve Clinic—University Hospital Liege, B-4000 Liege, Belgium;

[4] Cardiothoracic and Vascular Department, Pisa University, 56126 Pisa, Italy;

[5] Cardiovascular Research Center Aalst, OLV Clinic, 9300 Aalst, Belgium;

[6] Center for Cardiological Innovation, Department of Cardiology, Oslo University Hospital, Rikshospitalet, 0372 Oslo, Norway;

[7] Centre Hospitalier Universitaire de Rennes, Inserm, University of Rennes, LTSI—UMR 1099, F-35000 Rennes, France;

[8] Centre for Cardiovascular Diseases, University Hospital of Brussels, B-1090 Brussels, Belgium;

[9] Department of Advanced Biomedical Sciences, Federico II, University Hospital, 80131 Naples, Italy;

[10] Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, 35122 Padua, Italy;

[11] Department of Cardiology, Antwerp University Hospital, 2650 Edegem, Belgium;

[12] Department of Cardiology, Herlev and Gentofte Hospital, University of Copenhagen, 2900 Copenhagen, Denmark;

[13] Department of Cardiology, Hospital Universitari Vall d’Hebron, 08035 Barcelona, Spain;

[14] Department of Cardiology, Medical Academy, Lithuanian University of Health Sciences, 44307 Kaunas, Lithuania;

[15] Department of Cardiology, Medical University of Lodz, 91347 Lodz, Poland;

[16] Department of Cardiology, University of Medicine and Pharmacy Carol Davila—Emergency and University Hospital, 050474 Bucharest, Romania;

[17] Department of Cardiology, University of Medicine and Pharmacy “Carol Davila”—Euroecolab, Emergency Institute for Cardiovascular Diseases “Prof. Dr. C. C. Iliescu”, Sos. Fundeni 258, 022328 Bucharest, Romania;

[18] Department of Cardiovascular Diseases, University Hospital Centre Zagreb, 10000 Zagreb, Croatia;

[19] Department of Cardiovascular Surgery, University Medical Centre Ljubljana, 1000 Ljubljana, Slovenia;

[20] Department of Clinical Physiology and Echocardiography—Heart Valve Clinic, Lille University Hospital, 59800 Lille, France;

[21] Department of Family Medicine, University of Szeged, H-6725 Szeged, Hungary;

[22] Department of Medical Biotechnologies, Division of Cardiology, University of Siena, 53100 Siena, Italy;

[23] Department of Noninvasive Functional Diagnostic and Imaging, National Heart Hospital, 1309 Sofia, Bulgaria;

[24] Department “Gailezers”, Riga East Clinical University Hospital, LV-1038 Riga, Latvia;

[25] Heart and Lung Center, Helsinki University Hospital and Helsinki University, 00100 Helsinki, Finland;

[26] Institute for Emergency Cardiovascular Diseases and Transplant of Targu Mures, 540136 Targu Mures, Romania;

[27] Institute of Cardiology, University Foundation of Cardiology, Porto Alegre 90620-000, Brazil;

[28] Korgialenio Benakio—Red Cross Hospital, 115 26 Athens, Greece;

[29] Non-Invasive Department, Heart Hospital—Hamad Medical Corporation, Doha 3050, Qatar;

[30] Ramazzini Hospital, 41012 Carpi, Italy;

[31] Section of Cardiology, Department of Medicine, University of Verona, 37126 Verona, Italy;

[32] UO Cardiologia, Ospedale Infermi di Rimini, 47923 Rimini, Italy;

[33] UOC Cardiologia/UTIC—“Santa Maria delle Grazie” Hospital Pozzuoli, 80078 Pozzuoli, Italy;

关键词: speckle tracking echocardiography;    left atrial strain;    reference point;    multi-centric study;    standardization;   

DOI  :  10.3390/diagnostics10110946

来源: DOAJ

【 摘 要 】

Two methods are currently available for left atrial (LA) strain measurement by speckle tracking echocardiography, with two different reference timings for starting the analysis: QRS (QRS-LASr) and P wave (P-LASr). The aim of MASCOT HIT study was to define which of the two was more reproducible, more feasible, and less time consuming. In 26 expert centers, LA strain was analyzed by two different echocardiographers (young vs senior) in a blinded fashion. The study population included: healthy subjects, patients with arterial hypertension or aortic stenosis (LA pressure overload, group 2) and patients with mitral regurgitation or heart failure (LA volume–pressure overload, group 3). Difference between the inter-correlation coefficient (ICC) by the two echocardiographers using the two techniques, feasibility and analysis time of both methods were analyzed. A total of 938 subjects were included: 309 controls, 333 patients in group 2, and 296 patients in group 3. The ICC was comparable between QRS-LASr (0.93) and P-LASr (0.90). The young echocardiographers calculated QRS-LASr in 90% of cases, the expert ones in 95%. The feasibility of P-LASr was 85% by young echocardiographers and 88% by senior ones. QRS-LASr young median time was 110 s (interquartile range, IR, 78-149) vs senior 110 s (IR 78-155); for P-LASr, 120 s (IR 80-165) and 120 s (IR 90-161), respectively. LA strain was feasible in the majority of patients with similar reproducibility for both methods. QRS complex guaranteed a slightly higher feasibility and a lower time wasting compared to the use of P wave as the reference.

【 授权许可】

Unknown