The Central Role of Left Atrium in Heart Failure

Frontiers in Cardiovascular Medicine

Diego Fanti¹  Giovanni Benfari¹  Andrea Rossi¹  Flavio Luciano Ribichini¹  Simona Mega²  Maria Caterina Bono²  Francesco Grigioni²  Myriam Carpenito² 

[1] Section of Cardiology, Department of Medicine, University of Verona, Verona, Italy;Unit of Cardiac Sciences, Department of Medicine, Campus Bio-Medico University of Rome, Rome, Italy;

关键词: left atrium;    heart failure;    speckle-tracking echocardiography;    left atrial strain;    cardiovascular disease;    left atrial function;   

DOI  :  10.3389/fcvm.2021.704762

来源: DOAJ

【 摘 要 】

In past cardiovascular medicine, the attention to the left ventricle-identified as the only indicator and determinant of healthy or unhealthy cardiac conditions- has systematically hidden the role of the left atrium (LA). The recent advances in cardiovascular imaging have provided a better understanding of LA anatomy, physiology, and pathology, making us realize that this functional structure is far from being an innocent spectator. We now know that the LA's mechanical and neuro-hormonal properties play a relevant part in several cardiovascular diseases, including atrial fibrillation, ischemic heart disease, valvular heart disease, and heart failure. The present review aims to describe the role of LA in the specific setting of heart failure. We provide currently available information on LA structure and function and summarize its role as a determinant of symptoms, prognosis, and potential therapeutic target in heart failure patients.

【 授权许可】

Unknown