Digestive Responses to Fortified Cow or Goat Dairy Drinks: A Randomised Controlled Trial

Nutrients

卷:10

Karl Fraser¹  ColinG. Prosser²  ElizabethA. Carpenter²  AlisonJ. Hodgkinson³  SarahM. Mitchell⁴  David Cameron-Smith⁴  UtpalK. Prodhan⁴  AmberM. Milan⁴ 

[1] AgResearch Grasslands, Private Bag 11008, Palmerston North 4442, New Zealand;

[2] Dairy Goat Co-operative (NZ) Ltd., 18 Gallagher Dr, Melville, Hamilton 3206, New Zealand;

[3] Food and Bio-based Products, AgResearch, Private Bag 3123, Hamilton 3240, New Zealand;

[4] Liggins Institute, University of Auckland, 85 Park Road, Grafton, Private Bag 92019, Auckland 1023, New Zealand;

关键词: fortified milk;    goat milk;    nutrition;    adult;    protein hydrolysis;    digestion;    gastrointestinal;   

DOI  :  10.3390/nu10101492

来源: DOAJ

【 摘 要 】

Fortified milk drinks are predominantly manufactured from bovine (cow) sources. Alternative formulations include those prepared with hydrolysed bovine milk proteins or from alternate bovidae species, such as caprine (goat) milk. Currently, there is little data on protein digestive and metabolic responses following ingestion of fortified milk drinks. To examine the digestive and metabolic responses to commercially-available fortified milks, young adults (n = 15 males: 15 females), in a randomised sequence, ingested isonitrogenous quantities of whole cow-protein (WC), whole goat-protein (WG), or partially-hydrolysed whey cow-protein (HC), commercial fortified milks. Plasma amino acid (AA) and hormonal responses were measured at baseline and again at 5 h after ingestion. Paracetamol recovery, breath hydrogen, and subjective digestive responses were also measured. Postprandial plasma AA was similar between WC and WG, while AA appearance was suppressed with HC. Following HC, there was a negative incremental AUC in plasma branched-chain AAs. Further, HC had delayed gastric emptying, increased transit time, and led to exaggerated insulin and GLP-1 responses, in comparison to whole protein formulas. Overall, WC and WG had similar protein and digestive responses with no differences in digestive comfort. Contrastingly, HC led to delayed gastric emptying, attenuated AA appearance, and a heightened circulating insulin response.

【 授权许可】

Unknown