期刊论文详细信息
Molecules | 卷:18 |
Synthesis and Preliminary Biological Evaluations of 5′-Substituted Derivatives of Uridine as Glycosyltransferase Inhibitors | |
关键词: uridine; glycosyltransferase inhibitors; antifungal activity; | |
DOI : 10.3390/molecules18078018 | |
来源: DOAJ |
【 摘 要 】
New derivatives of uridine which contain a b-ketoenol motif were synthesized, characterized and biologically tested. Synthesized compounds 1–4 showed no activity against bovine milk β-1,4-galactosyltransferase I at concentrations up to 2.0 mM and were not active against Candida albicans and Aspergilus fumigatus up to the maximum tested concentration of 1,000 µg/mL.
【 授权许可】
Unknown