Calcium and Zinc Containing Bactericidal Glass Coatings for Biomedical Metallic Substrates

International Journal of Molecular Sciences

卷:15

José S. Moya¹  Leticia Esteban-Tejeda¹  Catuxa Prado²  Luis A. Díaz²  Ramón Torrecillas²  Belén Cabal² 

[1] Department of Biomaterials and Bioinspired Materials, Institute of Materials Science of Madrid (ICMM-CSIC), Cantoblanco, Madrid 28049, Spain;

[2] Nanomaterials and Nanotechnology Research Center (CINN-CSIC)—Universidad de Oviedo (UO) —Principado de Asturias, El Entrego, San Martín del Rey Aurelio 33940, Spain;

关键词: bactericidal glass;    biocompatible glass;    bactericidal glassy coating;    ZnO-glass;    soda-lime glass;    biometal coating;   

DOI  :  10.3390/ijms150713030

来源: DOAJ

【 摘 要 】

The present work presents new bactericidal coatings, based on two families of non-toxic, antimicrobial glasses belonging to B2O3–SiO2–Na2O–ZnO and SiO2–Na2O–Al2O3–CaO–B2O3 systems. Free of cracking, single layer direct coatings on different biomedical metallic substrates (titanium alloy, Nb, Ta, and stainless steel) have been developed. Thermal expansion mismatch was adjusted by changing glass composition of the glass type, as well as the firing atmosphere (air or Ar) according to the biomedical metallic substrates. Formation of bubbles in some of the glassy coatings has been rationalized considering the reactions that take place at the different metal/coating interfaces. All the obtained coatings were proven to be strongly antibacterial versus Escherichia coli (>4 log).

【 授权许可】

Unknown