Calcium and Zinc Containing Bactericidal Glass Coatings for Biomedical Metallic Substrates

International Journal of Molecular Sciences

Leticia Esteban-Tejeda¹  Luis A. D໚z²  Catuxa Prado²  Belén Cabal²  Ramón Torrecillas² 

[1] Department of Biomaterials and Bioinspired Materials, Institute of Materials Science of Madrid (ICMM-CSIC), Cantoblanco, Madrid 28049, Spain; E-Mails:;Nanomaterials and Nanotechnology Research Center (CINN-CSIC)—Universidad de Oviedo (UO) —Principado de Asturias, El Entrego, San Martín del Rey Aurelio 33940, Spain; E-Mails:

关键词: bactericidal glass;    biocompatible glass;    bactericidal glassy coating;    ZnO-glass;    soda-lime glass;    biometal coating;   

DOI  :  10.3390/ijms150713030

来源: mdpi

【 摘 要 】

The present work presents new bactericidal coatings, based on two families of non-toxic, antimicrobial glasses belonging to B₂O₃–SiO₂–Na₂O–ZnO and SiO₂–Na₂O–Al₂O₃–CaO–B₂O₃ systems. Free of cracking, single layer direct coatings on different biomedical metallic substrates (titanium alloy, Nb, Ta, and stainless steel) have been developed. Thermal expansion mismatch was adjusted by changing glass composition of the glass type, as well as the firing atmosphere (air or Ar) according to the biomedical metallic substrates. Formation of bubbles in some of the glassy coatings has been rationalized considering the reactions that take place at the different metal/coating interfaces. All the obtained coatings were proven to be strongly antibacterial versus Escherichia coli (>4 log).

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.