Synthesis of patterned enzyme–metal–organic framework composites by ink-jet printing

Bioresources and Bioprocessing

卷:4

Haotian Zhao¹  Jun Ge²  Yi Feng²  Miao Hou² 

[1] Beijing National Day School;

[2] Key Lab for Industrial Biocatalysis, Ministry of Education, Department of Chemical Engineering, Tsinghua University;

关键词: Immobilized enzyme;    Metal–organic frameworks;    Ink-jet printing;   

DOI  :  10.1186/s40643-017-0171-7

来源: DOAJ

【 摘 要 】

Abstract Objectives This report explores the possibility of synthesizing enzyme–metal–organic framework (MOF) composites by ink-jet printing. Results This study demonstrates that the direct synthesis of patterned enzyme–metal–organic framework (MOF) composites on various substrates including paper and polymeric films can be readily achieved by ink-jet printing bio-inks containing protein molecules, metal ions, and organic ligands loaded, respectively, in different cartridges. The formed Cytochrome c (Cyt c)–MOF composites on filter paper by ink-jet printing can be used for rapid detection of hydrogen peroxide in solution. Conclusions This technique opens possibilities of scalable, controllable, and designable fabrication of functional protein–MOF hybrid surface with promising applications in future bio-related application fields such as biosensing, wearable bioelectronics, artificial biomimetic membranes, and tissue engineering. Graphical abstract A direct synthesis of enzyme–MOF composites can be readily achieved by a ink-jet printing process

【 授权许可】

Unknown