Trichothecenes in Cereal Grains – An Update

Toxins

卷:11

Ana Badea¹  Maria Bürstmayr²  Hermann Bürstmayr²  Barbara Steiner²  Nehal Thakor³  TatianaY. Gagkaeva⁴  Danica Baines⁵  NoraA. Foroud⁵ 

[1] Brandon Research and Development Centre, Agriculture and Agri-Food Canada, Brandon, MB R7A 5Y3, Canada;

[2] Department of Agrobiotechnology (IFA-Tulln), Institute of Biotechnology in Plant Production, University of Natural Resources and Life Sciences, Vienna (BOKU), Tulln 3430, Austria;

[3] Department of Chemistry and Biochemistry, University of Lethbridge, Lethbridge, AB T1K 3M4, Canada;

[4] Laboratory of Mycology and Phytopathology, All-Russian Institute of Plant Protection (VIZR), St. Petersburg, Pushkin 196608, Russia;

[5] Lethbridge Research and Development Centre, Agriculture and Agri-Food Canada, Lethbridge, AB T1J 4B1, Canada;

关键词: deoxynivalenol;    t-2 toxin;    fusarium;    fusarium head blight (fhb);    wheat;    barley;    resistance;   

DOI  :  10.3390/toxins11110634

来源: DOAJ

【 摘 要 】

Trichothecenes are sesquiterpenoid mycotoxins produced by fungi from the order Hypocreales, including members of the Fusarium genus that infect cereal grain crops. Different trichothecene-producing Fusarium species and strains have different trichothecene chemotypes belonging to the Type A and B class. These fungi cause a disease of small grain cereals, called Fusarium head blight, and their toxins contaminate host tissues. As potent inhibitors of eukaryotic protein synthesis, trichothecenes pose a health risk to human and animal consumers of infected cereal grains. In 2009, Foroud and Eudes published a review of trichothecenes in cereal grains for human consumption. As an update to this review, the work herein provides a comprehensive and multi-disciplinary review of the Fusarium trichothecenes covering topics in chemistry and biochemistry, pathogen biology, trichothecene toxicity, molecular mechanisms of resistance or detoxification, genetics of resistance and breeding strategies to reduce their contamination of wheat and barley.

【 授权许可】

Unknown