Poor Clinical Sensitivity of Rapid Antigen Test for Influenza A Pandemic (H1N1) 2009 Virus

Emerging Infectious Diseases

卷:15

关键词: Influenza;    viruses;    influenza virus A (H1N1);    rapid antigen-based test;    real-time PCR;    sensitivity;   

DOI  :  10.3201/eid1510.091186

来源: DOAJ

【 摘 要 】

Influenza A pandemic (H1N1) 2009 virus RNA was detected by reverse transcription–PCR in 144 clinical samples from Bonn, Germany. A common rapid antigen–based test detected the virus in only 11.1% of these samples. The paramount feature of rapid test–positive samples was high virus concentration. Antigen-based rapid tests appear unsuitable for virologic diagnostics in the current pandemic.

【 授权许可】

Unknown