Metabolites Identification of Curcumin, Demethoxycurcumin and Bisdemethoxycurcumin in Rats After Oral Administration of Nanoparticle Formulations by Liquid Chromatography Coupled with Mass Spectrometry

World Journal of Traditional Chinese Medicine

卷:2

Min Ye¹  Rui Li¹  Cheng Xiang¹  Jing-Ran Fan¹  Jun-Bin He¹  Qi Wang¹  De-An Guo¹  Xue Qiao¹ 

[1] State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Beijing 100191, China;

关键词: Curcumin;    Demethoxycurcumin;    Bisdemethoxycurcumin;    Solid lipid nanoparticles;    Metabolic pathway;   

DOI  :  10.15806/j.issn.2311-8571.2016.0035

来源: DOAJ

【 摘 要 】

Background: Curcuminoids are promising cancer chemopreventive agents. Curcumin, demethoxycurcumin (DMC) and bisdemethoxycurcumin (BDMC) are the major bioactive curcuminoids in turmeric. However, comprehensive metabolic studies of these three curcuminoids are still limited.

【 授权许可】

Unknown