Multimodal imaging in acute retinal ischemia: spectral domain OCT, OCT-angiography and fundus autofluorescence

International Journal of Ophthalmology

卷:11

Mathias Maier¹  Daniel Zapp¹  Lukas Reznicek¹  Chris P. Lohmann¹  Christian S. Mayer¹  Nikolaus Feucht¹ 

[1] Department of Ophthalmology, Technical University of Munich, Munich 81675, Germany;

关键词: 1527;    optical coherence tomography;    optical coherence tomography-angiography;    acute retinal ischemia;    retinal morphology;    retinal blood flow;    multimodal retinal imaging;   

DOI  :  10.18240/ijo.2018.09.15

来源: DOAJ

【 摘 要 】

AIM: To describe retinal findings of various imaging modalities in acute retinal ischemia.METHODS: Fluorescein angiography (FA), spectral domain optical coherence tomography (SD-OCT), OCT-angiography (OCT-A) and fundus autofluorescence (FAF) images of 13 patients (mean age 64y, range 28-86y) with acute retinal ischemia were evaluated. Six suffered from branch arterial occlusion, 2 had a central retinal artery occlusion, 2 had a combined arteriovenous occlusions, 1 patient had a retrobulbar arterial compression by an orbital haemangioma and 2 patients showed an ocular ischemic syndrome.RESULTS: All patients showed increased reflectivity and thickening of the ischemic retinal tissue. In 10 out of 13 patients SD-OCT revealed an additional highly reflective band located within or above the outer plexiform layer. Morphological characteristics were a decreasing intensity with distance from the fovea, partially segmental occurrence and manifestation limited in time. OCT-A showed a loss of flow signal in the superficial and deep capillary plexus at the affected areas. Reduced flow signal was detected underneath the regions with retinal edema. FAF showed areas of altered signal intensity at the posterior pole. The regions of decreased FAF signal corresponded to peri-venous regions.CONCLUSION: Multimodal imaging modalities in retinal ischemia yield characteristic findings and valuable diagnostic information. Conventional OCT identifies hyperreflectivity and thickening and a mid-retinal hyperreflective band is frequently observed. OCT-A examination reveals demarcation of the ischemic retinal area on the vascular level. FAF shows decreased fluorescence signal in areas of retinal edema often corresponding to peri-venous regions.

【 授权许可】

Unknown