Successful use of intravitreal and systemic colistin in treating multidrug resistant Pseudomonas aeruginosa post-operative endophthalmitis

Indian Journal of Ophthalmology

卷:62

关键词: Malignant glaucoma;    pseudophakic;    surgical management;    zonulo-hyaloido-vitrectomy;    Automated retinal imaging;    diabetic retinopathy;    screening;    Low vision;    low vision aids;    quality of life;    Children;    congenital cataract;    hydrophobic acrylic intraocular lens;    intraocular lens implantation;    myopic shift;    polymethyl methacrylate;    Cost-effectiveness;    glaucoma;    pharmacoeconomics;    External limiting membrane;    macular hole;    predictors;    Optic nerve head drusen;    optical coherence tomography;    papilledema;    pseudopapilloedema;    Crowding;    logMAR chart;    refractive error;    screening;    visual acuity;    Acute retinal pigment epithelitis;    multifocal electroretinogram;    optical coherence tomography;    Anterior chamber;    intraocular parasite;    Linguatula serrata (tongue worm);    subluxated lens;    vitrectomy;    Carbonic anhydrase inhibitor;    Danon disease;    ERG;    retinal disease;    SD-OCT;    Levodopa;    occlusion amblyopia;    reverse amblyopia;    Acute angle closure glaucoma;    ciliochoroidal effusion;    oseltamivir;    transient myopia;    Cataract;    colistin;    endophthalmitis;    Pseudomonas aeruginosa;   

DOI  :  10.4103/0301-4738.126991

来源: DOAJ

【 摘 要 】

We report a case series of post-operative endophthalmitis due to Pseudomonas aeruginosa. A total of 8 patients operated for cataract, were referred to our facility with acute onset of decreased vision 1-2 days following surgery. All patients had clinical evidence of acute exogenous endophthalmitis with severe anterior chamber exudative reaction. Ocular samples (aqueous aspirate and vitreous tap) for microbiology were taken from all eyes. Microbiology from all revealed P. aeruginosa which was resistant to all antibiotics except colistin. With prompt and accurate microbiological support it was possible to control the infection in all the eyes with the use of colistin intravitreally and intravenously which to the best of our knowledge, has been never reported. Intravitreal injection of colistin could be an option effective in the management of multi-drug-resistant endophthalmitis caused by Gram-negative bacteria.

【 授权许可】

Unknown