Birdshot retinochoroiditis in Brazil: a multicenter review of 40 patients

International Journal of Retina and Vitreous

Remo T. Moraes¹  Moyses E. Zajdenweber¹  Juliana L. Oréfice²  Maria A. M. Frazão³  Luciana B. Carneiro⁴  Lilia R. P. Muralha⁵  Fernanda B. O. Porto⁶  Rodrigo L. Meirelles⁷  Joyce H. Yanamoto⁷  Eduardo Morizot⁸  Arnaldo Cialdini⁹  Daniel R. Lucena^1,10  Maria Luisa Gois da Fonsêca^1,11  Raul N. G. Vianna^1,11  Elaine Castro^1,11  Daniela S. da Costa^1,12  Sidney R. Lemos^1,13  Daniel V. Vasconcelos-Santos^1,13  Anna C. H. Rocha^1,13  Felipe T. Diligenti^1,14  Cristina Muccioli^1,15  Heloisa Nascimento^1,15  Luciana P. S. Finamor^1,15  Ever E. C. Rodriguez^1,15  Mario Motta^1,16  Mario J. Nobrega^1,17  Antonio M. B. Casella^1,18  Wilton Feitosa de Araújo^1,19 

[1]Brazilian Institute of Ophthalmology (IBOL), Rio de Janeiro, RJ, Brazil

[2]Centro Brasileiro de Ciências Visuais, Belo Horizonte, MG, Brazil

[3]Department of Ophthalmology, “Santa Casa”of São Paulo, São Paulo, SP, Brazil

[4]Fundação de Olhos de Góias (FUBOG), Goiânia, GO, Brazil

[5]Hospital de Olhos de Niterói, Niterói, RJ, Brazil

[6]INRET-Clinica e Centro de Pesquisa, Belo Horizonte, MG, Brazil

[7]Ophthalmology Department, Hospital das Clínicas, HCFMUSP (USP), São Paulo, SP, Brazil

[8]Retina and Vitreous Service, Botafogo Polyclinic, Rio de Janeiro, RJ, Brazil

[9]Retina and Vitreous Service, Brazilian Center for Eye Surgery (CBCO), Goiânia, GO, Brazil

[10]Retina and Vitreous Service, Escola Cearence de Oftalmologia, Fortaleza, CE, Brazil

[11]Retina and Vitreous Service, Federal Fluminense University (UFF), Marques do Parana Avenue 303 Centro, 24033900, Niterói, RJ, Brazil

[12]Retina and Vitreous Service, Federal Hospital of State Servers (SERVIDORES), Rio de Janeiro, RJ, Brazil

[13]Retina and Vitreous Service, Federal University of Minas Gerais (UFMG), Belo Horizonte, MG, Brazil

[14]Retina and Vitreous Service, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil

[15]Retina and Vitreous Service, Federal University of São Paulo (UNIFESP), São Paulo, SP, Brazil

[16]Retina and Vitreous Service, Federal University of the State of the Rio de Janeiro (UNIRIO), Rio de Janeiro, RJ, Brazil

[17]Retina and Vitreous Service, Hospital de Olhos Sadalla Amin Ghanem, Joinville, SC, Brazil

[18]Retina and Vitreous Service, Londrina State University (UEL), Londrina, PR, Brazil

[19]Retina and Vitreous Service, Santa Casa de Belo Horizonte, Belo Horizonte, MG, Brazil

关键词: Birdshot retinochoroiditis;    Retina;    Uveitis;   

DOI  :  10.1186/s40942-021-00353-1

来源: Springer

【 摘 要 】

BackgroundBirdshot retinochoroiditis (BRC) is a rare and chronic bilateral uveitis mostly found in Caucasians. As few data are available about the clinical course of BRC in Hispanic patients, we aimed to report the clinical findings and the evolution of BRC in Brazilian patients.MethodsThis retrospective cohort multicenter nationwide study was performed by analyzing the records of patients with BRC diagnoses from Brazilian ophthalmological centers from April 1995 to May 2020.ResultsForty patients (80 eyes) with a diagnosis of BRC were evaluated. The mean age was 53 years, and there was no sex predominance. All tested patients (34/40) were positive for HLA-A29. The diagnosis of BRC was made following the Levinson et al. criteria, and all ancillary tests were performed to exclude differential diagnoses. Clinical signs and symptoms, such as complications and treatment, were described.ConclusionsBRC evolution in Brazilian patients seems to have some peculiarities that diverge from the published literature available about Caucasians, as AS inflammation is higher in this population.

【 授权许可】

CC BY