Amputation of a type II diabetic patient with cutaneous leishmaniasis due to Leishmania major

BMC Infectious Diseases

Amina Bendjaballah-Laliam¹  Denis Sereno²  Ihcene Kherachi Djenad³  Zoubir Harrat³  Mohammad Akhoundi⁴  Arezki Izri⁵ 

[1] Etablissement Public Hospitalier de Hadjout, Tipaza, Algérie;Institut de Recherche Pour le Développement, Montpellier University, MIVEGEC, 34032, Montpellier, France;Institut de Recherche Pour le Développement, Montpellier University, InterTryp, 34032, Montpellier, France;Laboratoire d’Eco-épidemiologie Parasitaire et Génétique des Populations, Institute Pasteur of Algeria, Route du Petit Staoueli Dely Brahim, Algiers, Algeria;Parasitology-Mycology Department, Avicenne Hospital, AP-HP, 125, Route de Stalingrad, 93009, Bobigny Cedex, France;Parasitology-Mycology Department, Avicenne Hospital, AP-HP, 125, Route de Stalingrad, 93009, Bobigny Cedex, France;Unité des Virus Émergents (UVE: Aix-Marseille Univ-IRD 190-Inserm 1207-IHU Méditerranée Infection), Marseille, France;

关键词: Zoonotic cutaneous leishmaniasis;    Leishmania major;    Diabetes mellitus;    Amputation;   

DOI  :  10.1186/s12879-021-06909-8

来源: Springer

【 摘 要 】

BackgroundLeishmaniases are neglected tropical diseases of public health concern in Algeria. The immunocompromised patients with HIV, autoimmune diseases, or chronic alcohol abuse are at a higher risk of leishmaniasis. Herein, we present the case of an immunocompetent diabetic patient infected by Leishmania major, leading to life-threatening consequences.Case presentationAn Algerian diabetic patient developed a cutaneous lesion with large polymorphous inflamed granuloma and pyoderma gangrenosum in the left foot, following L. major infection. A delayed follow-up led to a treatment failure, resulting in the amputation.ConclusionsThis report highlights the absence of timely treatment of Leishmania infection as a life-threatening point among high-risk diabetic patients. Clinicians should be aware of this parasitosis leading to severe complications in diabetic patients.

【 授权许可】

CC BY