Animated, video entertainment-education to improve vaccine confidence globally during the COVID-19 pandemic: an online randomized controlled experiment with 24,000 participants

Trials

Zhuoran Wang¹  Haitao Liu¹  Chen Wang²  Peixin Wu³  Fengyun Yu⁴  Pascal Geldsetzer⁵  Maya Adam⁶  Sebastian Forster⁷  Shannon McMahon⁷  Simiao Chen⁸  Till Bärnighausen⁹  Jennifer Gates^1,10  Lirui Jiao^1,11  Juntao Yang^1,12  Qiushi Chen^1,13 

[1] Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China;Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China;National Clinical Research Center for Respiratory Diseases, Beijing, China;Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China–Japan Friendship Hospital, Beijing, China;Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China;Peking Union Medical College Hospital, Beijing, China;Department of Industrial Engineering, Tsinghua University, Beijing, China;Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA;Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA;Heidelberg Institute of Global Health (HIGH), Faculty of Medicine and University Hospital, Heidelberg University, Heidelberg, Germany;Heidelberg Institute of Global Health (HIGH), Faculty of Medicine and University Hospital, Heidelberg University, Heidelberg, Germany;Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China;Heidelberg Institute of Global Health (HIGH), Faculty of Medicine and University Hospital, Heidelberg University, Heidelberg, Germany;Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China;Department of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, MA, USA;Africa Health Research Institute (AHRI), Somkhele, KwaZulu-Natal, South Africa;Icahn School of Medicine at Mount Sinai, New York, NY, USA;Reed College, Portland, OR, USA;State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China;The Harold and Inge Marcus Department of Industrial and Manufacturing Engineering, The Pennsylvania State University, University Park, PA, USA;

关键词: COVID-19;    Rrandomized controlled trial;    Vaccine hesitancy;    Vaccine acceptance;    Protocol;    Hope;    List experiment;    Vaccine confidence;   

DOI  :  10.1186/s13063-022-06067-5

来源: Springer

【 摘 要 】

BackgroundScience-driven storytelling and entertainment-education (E-E) media demonstrate potential for promoting improved attitudes and behavioral intent towards health-related practices. Months after the outbreak of coronavirus disease 2019 (COVID-19), emerging research highlights the essential role of interventions to improve public confidence in the COVID-19 vaccine. To improve vaccine confidence, we designed three short, animated videos employing three research-informed pedagogical strategies. These can be distributed globally through social media platforms, because of their wordless and culturally accessible design. However, the effectiveness of short, animated storytelling videos, deploying various pedagogic strategies, needs to be explored across different global regions.Methods/designThe present study is a multi-site, parallel group, randomized controlled trial (RCT) comparing the effectiveness of (i) a storytelling-instructional-humor approach, (ii) a storytelling-analogy approach, (iii) a storytelling-emotion-focused approach, and (iv) no video. For our primary outcomes, we will measure vaccine hesitancy, and for secondary outcomes, we will measure behavioral intent to seek vaccination and hope. Using online platforms, we will recruit 12,000 participants (aged 18–59 years) from the USA and China, respectively, yielding a total sample size of 24,000.DiscussionThis trial uses innovative online technology, reliable randomization algorithms, validated survey instruments, and list experiments to establish the effectiveness of three short, animated videos employing various research-informed pedagogical strategies. Results will be used to scientifically support the broader distribution of these short, animated video as well as informing the design of future videos for rapid, global public health communication.Trial registrationGerman Clinical Trials Register DRKS #00023650. Date of registration: 2021/02/09.

【 授权许可】

CC BY