European Journal of Medical Research | |
Low-dose radiation treatment for painful plantar enthesophyte: a highly effective therapy with little side effects | |
Martijn van Griensven1  Freddy Djiepmo2  Wilfried Budach2  Judith Neuwahl2  Christiane Matuschek2  Bálint Tamaskovics2  Danny Jazmati2  Jan Haussmann2  Amir Rezazadeh2  Livia Schmidt2  Kimia Karimi2  Kitti Maas2  Edwin Bölke3  Stefanie Corradini4  Roman Gelzhäuser5  Matthias Peiper6  Christoph Schleich7  Klaus Orth8  | |
[1] Department cBITE, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University, Maastricht, The Netherlands;Department of Radiation Oncology, Heinrich Heine University, Dusseldorf, Germany;Department of Radiation Oncology, Heinrich Heine University, Dusseldorf, Germany;Klinik Für Strahlentherapie Und Radiologische Onkologie, Heinrich-Heine-Universität, Moorenstr. 5, 40225, Düsseldorf, Germany;Department of Radiation Oncology, University Hospital, LMU Munich, Munich, Germany;Institute of Mathematical Statistics and Probability Theory, Heinrich-Heine-University, Dusseldorf, Germany;Medical Faculty, Heinrich-Heine-University, Dusseldorf, Germany;Radiology Dusseldorf/Viersen, Ernst-Schneider-Platz 1, Dusseldorf, Germany;University of Hannover, Hannover, Germany; | |
关键词: Plantar enthesophyte; Heel spur; Radiation therapy; Benign disease; Pain; Photon therapy; Electrons; | |
DOI : 10.1186/s40001-022-00642-x | |
来源: Springer | |
【 摘 要 】
AimPlantar enthesophyte is a common degenerative disorder. Surgical and medical treatment options are associated with either poor outcome or high percentage of relapse. Observations have indicated a beneficial effect of radiation therapy. We therefore wanted to evaluate pain reduction using orthovolt or cobalt-based radiation treatment for painful plantar enthesophyte and determine long-term response as well as prognostic parameters in this condition.MethodsWe identified a total of 102 consecutive patients treated for a total of 117 symptomatic heel spurs. 59 patients were treated with cobalt radiation, 31 patients with orthovolt therapy and 12 patients with both radiation systems. Primary outcome measure was pain reduction being scored using the modified Rowe Score prior therapy, at the end of each treatment series as well as after 6 weeks. Secondary outcome measure was long-term outcome, evaluated in patients with a follow-up period of longer than 3 years.ResultsBefore radiation therapy, 61 patients (60.4%) had a score of 0, significant strong pain. At the time of completion of radiation treatment, 3 patients (2.7%) were pain-free (score of 30), whereas 8 patients (7.9%) had still severe pain (score 0). 6 weeks after radiation therapy, 33 patients (32.7%) were pain-free and 8 patients (7.9%) had severe pain (score 0), while at the time data of collection, 74 patients (73%) were free of pain and 1 patient (1%) had strong pain (score 0). Duration of pain before the start of radiation treatment was a significant prognostic factor (p = 0.012) for response to treatment.ConclusionRadiotherapy of painful plantar enthesophyte is a highly effective therapy with little side effects providing long-term therapeutic response. The only significant prognostic parameter for response to treatment is the duration of pre-radiation therapy pain. Early integration of radiation therapy in the treatment seems to result in superior pain reduction.
【 授权许可】
CC BY
【 预 览 】
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