The tumor suppressor Zinc finger protein 471 suppresses breast cancer growth and metastasis through inhibiting AKT and Wnt/β-catenin signaling

Clinical Epigenetics

Lili Li¹  Thomas C. Putti²  Shujun Feng³  Tingxiu Xiang⁴  Guosheng Ren⁴  Zhu Qiu⁴  Juan Luo⁴  Danfeng Zhou⁴  Chunfang Tao⁴  Jun Tang⁴  Qiao Tao⁵ 

[1] Cancer Epigenetics Laboratory, Department of Clinical Oncology, State Key Laboratory of Translational Oncology, Sir YK Pao Center for Cancer and Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong and CUHK Shenzhen Research Institute, Hong Kong, China;Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore;Hunan Province Key Laboratory of Tumor Cellular and Molecular Pathology, Cancer Research Institute, Hengyang School of Medicine, University of South China, Hengyang, China;Key Laboratory of Molecular Oncology and Epigenetics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China;Key Laboratory of Molecular Oncology and Epigenetics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China;Cancer Epigenetics Laboratory, Department of Clinical Oncology, State Key Laboratory of Translational Oncology, Sir YK Pao Center for Cancer and Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong and CUHK Shenzhen Research Institute, Hong Kong, China;

关键词: ZNF471;    CpG methylation;    Breast;    AKT;    Wnt signaling;   

DOI  :  10.1186/s13148-020-00959-6

来源: Springer

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